Tiny Earth inspires and retains students in the sciences while addressing one of the most pressing global health challenges of our century—the diminishing supply of effective antibiotics. Tiny Earthlings are college students who enroll in a Tiny Earth research course to discover antibiotics from soil bacteria in their own backyards. This innovative, international network was created by Dr. Jo Handelsman, Vilas Research Professor of Plant Pathology at the University of Wisconsin-Madison and former Associate Director for Science at the White House Office of Science and Technology Policy (OSTP).